| February 2001 |
Perseus Proteomics Inc. was established in Bunkyo-ku, Tokyo. |
| October 2002 |
Began selling antibodies as research reagents. |
| April 2003 |
Participated in the Protein Interaction Analysis Nano-Biochip Project of the New Energy and Industrial Technology Development Organization (NEDO). |
| July 2003 |
Relocated its head office to Shibuya-ku, Tokyo. |
| August 2004 |
Entered into a distribution agreement with R&D Systems Inc. for research reagents and began global sales. |
| September 2004 |
Relocated its head office to Meguro-ku, Tokyo. |
| September 2005 |
Began selling antibodies targeting all 48 nuclear receptors. |
| September 2006 |
Entered into an agreement with Chugai Pharmaceutical Co., Ltd. to transfer the right to obtain patents and other rights related to the anti-glypican 3 antibody PPMX-T001. |
| September 2008 |
Launched the PTX3 ELISA Kit as a research reagent. |
| November 2008 |
A Phase I clinical trial of the anti-glypican 3 antibody PPMX-T001 began in the United States. |
| January 2009 |
Through a third-party allotment of new shares, FUJIFILM Corporation acquired 76.68% of the Company’s shares and became its parent company. |
| January 2011 |
Licensed out PPMX-T002, a radioisotope-labeled anti-cadherin 3 antibody (Note 2) , to FUJIFILM Corporation. |
| December 2014 |
The anti-transferrin receptor antibody PPMX-T003 was selected as a supported project under the Japan Science and Technology Agency (JST)’s Program on Open Innovation Platform with Enterprises, Research Institute and Academia, Acceleration Type (Drug Discovery). |
| September 2015 |
Licensed out PPMX-T004, an antibody-drug conjugate targeting cadherin 3, to FUJIFILM Corporation. |
| January 2016 |
A Phase I clinical trial of PPMX-T002, a radioisotope-labeled anti-cadherin 3 antibody, began in the United States. |
| March 2018 |
Following a third-party allotment of new shares, FUJIFILM Corporation’s shareholding in the Company decreased to 48.62%, making FUJIFILM Corporation an “other associated company” of the Company. |
| January 2019 |
Opened the Nagoya Laboratory in Chikusa-ku, Nagoya, Aichi Prefecture, to maintain and further develop its phage display technology and to promote research and development of antibody drugs. |
| November 2019 |
The first in-house clinical trial, a Phase I clinical trial of the anti-transferrin receptor antibody PPMX-T003 for polycythemia vera, began in Japan. |
| April 2020 |
A Phase I clinical trial of PPMX-T002, a radioisotope-labeled anti-cadherin 3 antibody anticancer drug, began in Japan. |
| June 2021 |
Listed on the Mothers Market of the Tokyo Stock Exchange. |
| March 2022 |
Research and development of PPMX-T003 for aggressive NK-cell leukemia (ANKL) was selected as a project under AMED’s Practical Application Support Program before being designated as Orphan Drug, under the Drug Discovery Support Promotion Project, in FY2022.
|
| March 2022 |
Terminated license agreements with FUJIFILM Corporation for PPMX-T002 and PPMX-T004. |
| April 2022 |
Following the Tokyo Stock Exchange’s market restructuring, the Company transitioned from the Mothers Market to the Growth Market. |
| September 2022 |
FUJIFILM Corporation ceased to be an “other associated company” of the Company. |
| March 2023 |
A clinical trial notification for an investigator-initiated Phase I/II clinical trial of PPMX-T003 for ANKL was submitted and approved. |
| July 2023 |
Relocated its head office to Chuo-ku, Tokyo. |
| February 2025 |
Research and development of PPMX-T003 for ANKL was selected as a project under AMED’s Practical Application Support Program before being designated as Orphan Drug, under the Drug Discovery Support Promotion Project, in FY2025. |
| May 2025 |
Launched its “VHH Antibody Library-Based Screening and Production” service as part of its antibody research support offerings. |